Technology Development & Transfer
Build the Cell Technology Your Program Needs
Not every organization needs to license an existing therapeutic product. Some need the capability to build their own.
Decinova develops cell and regenerative-medicine technologies around partner requirements and can support their implementation within research, development or manufacturing environments.
The objective is not simply to provide cells. It is to establish a reproducible technology platform that the partner can understand, operate and further develop.
Technology Platforms
Depending on Project Objectives and Feasibility
Bone Marrow-Derived Stromal Cells
Process development covering isolation, expansion, characterization, cryopreservation and related quality considerations.
Adipose-Derived Stromal Cells
Development and optimization of stromal-cell processes derived from adipose tissue.
Wharton’s Jelly Stromal Cells
Development of umbilical-cord / Wharton’s Jelly-derived stromal-cell platforms for research and translational applications.
Placental & Cord-Derived Technologies
Development of selected perinatal tissue-derived cell platforms based on project requirements and intended application.
Extracellular Vesicles / Exosomes
Development of EV-related workflows including producer-cell strategy, culture and collection approaches, isolation/purification strategy, characterization and process-development considerations.
Custom Cell Platforms
Assessment and development of additional cell-based technologies where Decinova’s translational capabilities are relevant.
From Protocol to Platform
A Technology-Transfer Project May Include:
Define
- Intended application
- Product concept
- Facility capabilities
- Scale requirements
- Quality requirements
- Development objective
Develop
- Cell source
- Isolation
- Culture conditions
- Expansion
- Process optimization
- Cryopreservation
- Harvest & formulation
Characterize
- Identity
- Purity
- Viability
- Phenotype
- Functional characterization
- Potency concepts
- QC strategy
Document
- Process documentation
- SOPs
- Batch documentation concepts
- Analytical procedures
- Training materials
- Technology-transfer package
Transfer
- On-site or structured remote transfer
- Personnel training
- Process implementation
- Engineering runs
- Troubleshooting
- Qualification support as appropriate
Technology Transfer Is More Than a Protocol
A Written Protocol Rarely Captures the Practical Knowledge Required to Reproduce a Biological Process
Successful technology transfer requires understanding which parameters are critical, where variability occurs, what can be modified and what must remain controlled.
Decinova combines documented procedures with practical process knowledge and training to help partners establish robust internal capability.
Custom Development
Your Starting Point Determines the Program
A partner may arrive with:
- An early scientific concept
- An existing laboratory protocol
- A partially developed process
- A technology requiring optimization
- Or simply a defined need for a cell platform that does not yet exist
Decinova structures the development program around that starting point.
The first step is therefore not selecting a standard package. It is defining the technology, intended application and development endpoint.
Build Capability, Not Dependence
Our objective in technology-transfer projects is to leave the partner with more than a supplied biological material. Where project scope allows, the intended outcome is a functioning technology platform supported by process knowledge, documentation and trained personnel.